Restarting Anticoagulation After Hemorrhage With or Without Reversal

We have accepted that while NOACs (non-vitamin K-dependent oral anticoagulants) are associated with fewer major bleeding complications than warfarin, the fact remains that one cannot treat a patient with an anticoagulant (or, for that matter, an anti-platelet agent—and certainly both!) without increasing that patient’s bleeding risk from baseline. Hopefully, the...

Breast Cancer and Interprofessional Care

In 1999, the IOM’s landmark report To Err is Human: Building a Safer Health System, explored the impact of medical errors on clinical outcomes in terms of human lives.1 Importantly, recommendations from that report included establishing interdisciplinary team training and implementing an interdisciplinary, collaborative approach to re-designing complex systems of...

What is THC?

The pharmacology of (−)-trans-Δ⁹-tetrahydrocannabinol, or THC, is probably the most well-studied of any controlled substance. THC has both psychoactive and peripheral physiologic effects in man, but it is best known as the component of marijuana that causes a “high”. THC is the most common phytocannabinoid (plant-derived cannabinoid) in cannabis drug...