What is ABSSSI?

(a) The most abominable medical acronym ever (b) The most challenging tongue-twister in the Romulan language (c) Regulatory-speak from the US FDA (d) a 1989 American science fiction film written and directed by James Cameron and starring Ed Harris and Mary Elizabeth Mastrantonio (e) (a) and (c) (f) (b) and...

The Human Endocannabinoid System

The endogenous cannabinoid (or “endocannabinoid”) system is a complex, widely dispersed neuromodulatory system that some consider to have the ultimate responsibility for “homeostasis” (that is, the maintenance of “steady state,” or “normal”) in the human body. Homeostasis has also been called “biological harmony in response to changes in the environment.”1...

VKA vs NOAC

The title represents the ultimate alphabet soup, no? Most practicing physicians, however, would recognize these acronyms and have probably committed to one or the other as a preferred agent in their own patient management decisions. VKAs and NOACs are anticoagulants—that is, they prevent blood from clotting properly, which is a...